Mueller matrix polar decomposition (MMPD) is capable of extracting intrinsic polarimetric characteristics of tissue-like media, including the orientation angle of the linear retardance axis. Here we propose a modified MMPD parameter to calculate linear birefringence orientation for multi-layered media. By measuring different experimental layered phantoms designed by ourselves and pathological tissue slices, we demonstrate that the calibrated new parameter can show more accurately the fast axis orientation angle. Since the multi-layered anisotropic structures are widely distributed in biomedical samples, we believe that the parameter proposed in this study can be helpful for future biomedical diagnosis.

Date Published: 9 March 2020
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Proc. SPIE 11238, Optical Interactions with Tissue and Cells XXXI, 112380O (9 March 2020); doi: 10.1117/12.2545558

Published in SPIE Proceedings Vol. 11238:
Optical Interactions with Tissue and Cells XXXI
Bennett L. Ibey; Norbert Linz, Editor(s)