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Proceedings Paper

Analysis and calibration of linear birefringence orientation parameter derived from Mueller matrix for multi-layered tissues (Conference Presentation)
Author(s): Weipeng Li; Honghui He; Tao Sun; Hui Ma

Paper Abstract

Mueller matrix polar decomposition (MMPD) is capable of extracting intrinsic polarimetric characteristics of tissue-like media, including the orientation angle of the linear retardance axis. Here we propose a modified MMPD parameter to calculate linear birefringence orientation for multi-layered media. By measuring different experimental layered phantoms designed by ourselves and pathological tissue slices, we demonstrate that the calibrated new parameter can show more accurately the fast axis orientation angle. Since the multi-layered anisotropic structures are widely distributed in biomedical samples, we believe that the parameter proposed in this study can be helpful for future biomedical diagnosis.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11238, Optical Interactions with Tissue and Cells XXXI, 112380O (9 March 2020); doi: 10.1117/12.2545558
Show Author Affiliations
Weipeng Li, Tsinghua Univ. (China)
Honghui He, Tsinghua Univ. (China)
Tao Sun, Tsinghua Univ. (China)
Hui Ma, Tsinghua Univ. (China)

Published in SPIE Proceedings Vol. 11238:
Optical Interactions with Tissue and Cells XXXI
Bennett L. Ibey; Norbert Linz, Editor(s)

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