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Proceedings Paper

Control of cell arrangement on PMMA surface by femtosecond laser induced periodic nanostructures
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Paper Abstract

We have experimentally shown that selective modification of the PMMA surface with a femtosecond laser irradiation could control the adhesion of cells to the PMMA surface. Using a femtosecond laser, periodic nanostructures were formed indirectly on a part of the PMMA film surface. By performing a cell cultivation test, the cell adhesion density to the substrate was measured. As a result, the cell adhesion density was 7 times higher in the laser processed area than in the non-processed area. This is considered to be due to the fact that the cell adhesive protein adheres well to the surface processed by the femtosecond laser.

Paper Details

Date Published: 3 April 2020
PDF: 8 pages
Proc. SPIE 11268, Laser-based Micro- and Nanoprocessing XIV, 1126805 (3 April 2020); doi: 10.1117/12.2545529
Show Author Affiliations
N. Shinohara, Osaka Univ. (Japan)
M. Tsukamoto, Osaka Univ. (Japan)
Y. Sato, Osaka Univ. (Japan)

Published in SPIE Proceedings Vol. 11268:
Laser-based Micro- and Nanoprocessing XIV
Udo Klotzbach; Akira Watanabe; Rainer Kling, Editor(s)

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