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Proceedings Paper

Elastic characterization of heterogeneous tissues using longitudinal shear waves in optical coherence elastography (Conference Presentation)
Author(s): Fernando Zvietcovich; Gary R. Ge; Humberto Mestre; Michael Giannetto; Maiken Nedergaard; Jannick P. Rolland; Kevin J. Parker

Paper Abstract

Longitudinal shear waves (LSW) are waves with longitudinally polarized displacement that travel at the shear wave speed through depth when generated at the surface of tissues. In this study, we explore LSW generated by a circular glass plate in contact with the sample. Results demonstrated the potential of LSW in detecting an elasticity gradient along axial (resolution < 0.13 mm) and lateral (resolution < 0.78 mm) directions simultaneously. Finally, LSWs are used for the elastography of ex vivo mouse brain and demonstrated differentiated LSW speed values between the cerebral cortex (2.91 m/s) and cerebellum/midbrain (1.18 m/s) regions.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420X (9 March 2020); doi: 10.1117/12.2545388
Show Author Affiliations
Fernando Zvietcovich, Univ. of Rochester (United States)
Gary R. Ge, Univ. of Rochester (United States)
Humberto Mestre, Univ. of Rochester (United States)
Michael Giannetto, Ctr. for Translational Neuromedicine (United States)
Maiken Nedergaard, Ctr. for Translational Neuromedicine (United States)
Jannick P. Rolland, The Institute of Optics (United States)
Kevin J. Parker, Univ. of Rochester (United States)


Published in SPIE Proceedings Vol. 11242:
Optical Elastography and Tissue Biomechanics VII
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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