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Proceedings Paper

Simultaneously imaging and quantifying in vivo mechanical properties of crystalline lens and cornea using optical coherence elastography with acoustic radiation force excitation (Conference Presentation)

Paper Abstract

The changes in biomechanical properties of lens and cornea are closely correlated with presbyopia and cataract. We developed an optical coherence elastography system utilizing acoustic radiation force excitation to simultaneously assess the elasticities of the crystalline lens and the cornea in vivo. A swept light source was integrated into the system to provide an enhanced imaging range that covers both the lens and the cornea. Additionally, the oblique imaging approach combined with orthogonal excitation also improved the image quality. Simultaneous elasticity measurements of lens and cornea were performed in anesthetized rabbits to demonstrate the capability of ARF-OCE to characterize in vivo elasticity in the anterior eye.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420Z (9 March 2020); doi: 10.1117/12.2545366
Show Author Affiliations
Yan Li, Univ. of California, Irvine (United States)
Jiang Zhu, Univ. of California, Irvine (United States)
Jason J. Chen, Univ. of California, Irvine (United States)
Qifa Zhou, The Univ. of Southern California (United States)
Zhongping Chen, Univ. of California, Irvine (United States)

Published in SPIE Proceedings Vol. 11242:
Optical Elastography and Tissue Biomechanics VII
Kirill V. Larin; Giuliano Scarcelli, Editor(s)

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