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Proceedings Paper

Endoscopic polarization-sensitive OCT using spun fiber (Conference Presentation)
Author(s): Saijun Qiu; Yan Li; Zhongping Chen

Paper Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) provides cross-sectional images of different polarization states, which can be utilized to obtain additional properties of biological tissue, such as birefringence. It has been demonstrated that collagen secreted by smooth muscle cells (SMC) is highly associated with the stability of atherosclerotic plaques; since both collagen and SMC are birefringent, endoscopic PS-OCT may provide a means to quantitatively analyze the risks and stability of atherosclerotic plaques. Here, we developed a compact spun-fiber-based PS-OCT to achieve robust imaging. In this work, the phase retardation map and OCT images of an ex vivo cadaver coronary artery are presented, and the birefringence of the collagen and SMC is identified.

Paper Details

Date Published: 6 March 2020
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Proc. SPIE 11214, Endoscopic Microscopy XV, 112140S (6 March 2020); doi: 10.1117/12.2545351
Show Author Affiliations
Saijun Qiu, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Yan Li, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 11214:
Endoscopic Microscopy XV
Guillermo J. Tearney M.D.; Thomas D. Wang; Melissa J. Suter, Editor(s)

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