Share Email Print
cover

Proceedings Paper

Development of a clinically translatable hyperspectral endoscopy (HySE) system and analysis methods for the improved diagnosis of gastrointestinal disease (Conference Presentation)
Author(s): Jonghee Yoon; Alexandru Grigoroiu; James Joseph; Dale J. Waterhouse; Siri Luthman; George Gordon; Massimiliano di Pietro; Wladyslaw Januszewicz; Rebecca C. Fitzgerald; Sarah E. Bohndiek

Paper Abstract

Hyperspectral imaging techniques measure spatial and spectral information, which enables discrimination between healthy tissue and lesions. Hyperspectral imaging applications in endoscopy for clinical diagnostic applications are still limited due to image distortion challenges that arise when working with a flexible endoscope, for example in the gastrointestinal tract. Here, we developed a hyperspectral endoscopy (HySE) system by exploiting a line-scanning spectrograph to measure spectral information at high spectral resolution and combining it with a CMOS camera that records wide-field images for hyperspectral image reconstruction. Moreover, we developed an image normalisation method using near-infrared light to obtain accurate hyperspectral signals by correcting uneven illumination conditions during clinical endoscopy. Our next step is to apply HySE to patients to identify abnormal features in the gastrointestinal tract in vivo.

Paper Details

Date Published: 9 March 2020
PDF
Proc. SPIE 11229, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII, 112291A (9 March 2020); doi: 10.1117/12.2545230
Show Author Affiliations
Jonghee Yoon, Univ. of Cambridge (United Kingdom)
Cancer Research UK Cambridge Institute (United Kingdom)
Alexandru Grigoroiu, Univ. of Cambridge (United Kingdom)
James Joseph, Univ. of Cambridge (United Kingdom)
Cancer Research UK Cambridge Institute (United Kingdom)
Dale J. Waterhouse, Univ. of Cambridge (United Kingdom)
Cancer Research UK Cambridge Institute (United Kingdom)
Siri Luthman, Univ. of Cambridge (United Kingdom)
George Gordon, The Univ. of Nottingham (United Kingdom)
Massimiliano di Pietro, Hutchison/MRC Research Ctr. (United Kingdom)
Wladyslaw Januszewicz, Hutchison/MRC Research Ctr. (United Kingdom)
Rebecca C. Fitzgerald, Hutchison/MRC Research Ctr. (United Kingdom)
Sarah E. Bohndiek, Univ. of Cambridge (United Kingdom)
Cancer Research UK Cambridge Institute (United Kingdom)


Published in SPIE Proceedings Vol. 11229:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII
Anita Mahadevan-Jansen, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray