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Proceedings Paper

Progress in angle-resolved low-coherence interferometry for real-time detection of epithelial dysplasia (Conference Presentation)

Paper Abstract

Angle-resolved low-coherence interferometry (a/LCI) is an optical technique which uses inverse models of light scattering to predict the size and density of cell nuclei, a significant biomarker of precancer. In recent years, substantial progress has occurred in a/LCI technology, particularly in novel instrumentation for the detection of dysplasia in the cervix and the esophagus. This abstract summarizes recent developments in a/LCI, with a focus on developments over the previous four years. Clinical studies in the cervix, novel optical instrumentation addressing the cervix and esophagus, and novel applications related to Alzheimer’s disease are discussed.

Paper Details

Date Published: 10 March 2020
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Proc. SPIE 11253, Biomedical Applications of Light Scattering X, 1125302 (10 March 2020); doi: 10.1117/12.2545173
Show Author Affiliations
Zachary A. Steelman, Duke Univ. (United States)
Derek Ho, Duke Univ. (United States)
Yang Zhao, Duke Univ. (United States)
Haoran Zhang, Duke Univ. (United States)
Evan Jelly, Duke Univ. (United States)
Ge Song, Duke Univ. (United States)
Wesley Y. Kendall, Duke Univ. (United States)
Michael Crose, Duke Univ. (United States)
Brian Cox, Duke Univ. (United States)
Kengyeh K. Chu, Duke Univ. (United States)
Adam P. Wax, Duke Univ. (United States)


Published in SPIE Proceedings Vol. 11253:
Biomedical Applications of Light Scattering X
Adam Wax; Vadim Backman, Editor(s)

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