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Proceedings Paper

Full resolution PS-OCT assessment of airway smooth muscle in a longitudinal bronchial thermoplasty study (Conference Presentation)
Author(s): David C. Adams; Jasmin A. Holz; Andrew F. McCrossan; Lida P. Hariri; Margit V. Szabari; Melissa J. Suter

Paper Abstract

The goal of bronchial thermoplasty (BT) is to reduce the symptoms associated with asthma by ablating the hyper-responsive airway smooth (ASM), but results have been mixed. In this work we present the results of a study in which we imaged canines before and after BT using polarization-sensitive optical coherence tomography (PS-OCT) in order to assess the potential of PS-OCT for use in conjunction with the BT procedure. By employing a novel processing technique we demonstrate PS-OCT results obtained at full system resolution, allowing us to accurately measure even vanishingly thin ASM distributions following the BT procedure.

Paper Details

Date Published: 6 March 2020
Proc. SPIE 11214, Endoscopic Microscopy XV, 112140C (6 March 2020); doi: 10.1117/12.2545139
Show Author Affiliations
David C. Adams, Massachusetts General Hospital (United States)
Jasmin A. Holz, Massachusetts General Hospital (United States)
Andrew F. McCrossan, Massachusetts General Hospital (United States)
Lida P. Hariri, Massachusetts General Hospital (United States)
Margit V. Szabari, Massachusetts General Hospital (United States)
Melissa J. Suter, Massachusetts General Hospital (United States)

Published in SPIE Proceedings Vol. 11214:
Endoscopic Microscopy XV
Guillermo J. Tearney M.D.; Thomas D. Wang; Melissa J. Suter, Editor(s)

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