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Proceedings Paper

Capillary refill: a technique for obtaining histology-grade OCT angiography maps of human dermal vasculature in vivo (Conference Presentation)
Author(s): Michael Evers; Malte Casper; Garuna Kositratna; Josh Glahn; Weeranut Phothong; Tuanlian Luo; Dieter Manstein

Paper Abstract

Optical coherence tomography angiography (OCTA) provides in-vivo images of microvasculature. In skin it often represents a dynamic perfusion state without depicting the actual extent of the vascular network. Here, we present the capillary refill method for obtaining a more accurate anatomic representation of surface capillary networks in human skin using OCTA. OCTA images were captured at baseline displaying ambient capillary perfusion and after compression and release of the skin representing the network of existing capillaries at full capacity. This method provides mapping of cutaneous capillary networks independent of ambient perfusion comparable to histological analysis of biopsies on identical skin sites.

Paper Details

Date Published: 6 March 2020
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Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 112110T (6 March 2020); doi: 10.1117/12.2545086
Show Author Affiliations
Michael Evers, Massachusetts General Hospital (United States)
Malte Casper, Columbia Univ. (United States)
Garuna Kositratna, Massachusetts General Hospital (United States)
Josh Glahn, Massachusetts General Hospital (United States)
Weeranut Phothong, Massachusetts General Hospital (United States)
Tuanlian Luo, Massachusetts General Hospital (United States)
Dieter Manstein, Massachusetts General Hospital (United States)


Published in SPIE Proceedings Vol. 11211:
Photonics in Dermatology and Plastic Surgery 2020
Bernard Choi; Haishan Zeng, Editor(s)

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