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Proceedings Paper

High-resolution multimodal flexible coherent Raman endoscope (Conference Presentation)
Author(s): Hervé Rigneault; Viktor Tsvirkun; Vasyl Mytskaniuk; Marc Fabert; Frédéric Louradour; Alexandre Kudlinski

Paper Abstract

We present a flexible, compact, and multimodal nonlinear endoscope (2.2 mm outer diameter) based on a resonantly scanned negative curvature hollow-core double-clad fiber. The fiber design allows distortion-less, background-free delivery of femtosecond and picosecond excitation pulses and the back-collection of nonlinear signals through the same fiber. Sub-micron spatial resolution together with large field of view is made possible by the combination of a miniature objective lens together with a silica microsphere lens inserted into the fiber core. We demonstrate coherent anti-Stokes Raman scattering, 2-photon fluorescence and second harmonic generation imaging at a rate of 10 frames/s.

Paper Details

Date Published: 10 March 2020
Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 112511C (10 March 2020); doi: 10.1117/12.2545038
Show Author Affiliations
Hervé Rigneault, Aix-Marseille Univ., CNRS (France)
Institut Fresnel (France)
Viktor Tsvirkun, Aix-Marseille Univ., CNRS (France)
Institut Fresnel (France)
Vasyl Mytskaniuk, Aix-Marseille Univ., CNRS (France)
Institut Fresnel (France)
Marc Fabert, Univ. de Limoges (France)
XLIM (France)
Frédéric Louradour, Univ. de Limoges (France)
XLIM (France)
Alexandre Kudlinski, Lab de Physique des Lasers, Atomes et Molécules (France)
Univ. de Lille (France)

Published in SPIE Proceedings Vol. 11251:
Label-free Biomedical Imaging and Sensing (LBIS) 2020
Natan T. Shaked; Oliver Hayden, Editor(s)

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