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Proceedings Paper

Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection (Conference Presentation)

Paper Abstract

We present advances in coherent Raman imaging for gastrointestinal cancer detection. We use stimulated Raman scattering (SRS) combined with second harmonic generation (SHG) to reveal cell nuclei, cytoplasm and collagen simultaneously in human tissues. Cell nuclei, cytoplasm and extra cellular matrix can be visualized in real time with image quality similar to conventional histology.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, 112360H (9 March 2020); doi: 10.1117/12.2544989
Show Author Affiliations
Hervé Rigneault, Aix Marseille Univ., CNRS (France)
Institut Fresnel (France)
Barbara Sarri, Aix Marseille Univ., CNRS (France)
Institut Fresnel (France)
Xavier Audier, Aix Marseille Univ., CNRS (France)
Institut Fresnel (France)
Julien Wojak, Aix Marseille Univ., CNRS (France)
Institut Fresnel (France)
Fabrice Caillol, Institut Paoli Calmettes (France)
Flora Poizat, Institut Paoli Calmettes (France)
Marc Giovannini, Institut Paoli Calmettes (France)


Published in SPIE Proceedings Vol. 11236:
Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry
Wolfgang Petrich; Zhiwei Huang, Editor(s)

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