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Proceedings Paper

PDMS-based Bragg diffraction grating glucose sensor integrable in a contact lens
Author(s): Carla Dumitrascu; Maria Morant; Laura Mercadé; Todora Angelova; Roberto Llorente
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Paper Abstract

This paper proposes a glucose optical biosensor based on a Bragg diffraction grating fabricated in Poly(dimethylsiloxane) (or PDMS), suitable for integration in an ophthalmologic contact lens. One of the periodic layers of the grating is functionalized with Glucose Oxidase (GOx) to change its refractive index proportionally with glucose concentration and, therefore, modify the response of the resulting filter. Different layers are fabricated and characterized by spectroscopic ellipsometry considering different glucose concentrations. The proposed structure can detect changes in glucose levels from 80 mg/dl to 180 mg/dl, reducing its optical response to 65% at 521 nm, being capable of real-time, continuous and non-invasive sensing.

Paper Details

Date Published: 20 February 2020
PDF: 8 pages
Proc. SPIE 11233, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX, 112330Q (20 February 2020); doi: 10.1117/12.2544876
Show Author Affiliations
Carla Dumitrascu, Univ. Politècnica de València (Spain)
Maria Morant, Univ. Politècnica de València (Spain)
Laura Mercadé, Univ. Politècnica de València (Spain)
Todora Angelova, Univ. Politècnica de València (Spain)
Roberto Llorente, Univ. Politècnica de València (Spain)


Published in SPIE Proceedings Vol. 11233:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX
Israel Gannot, Editor(s)

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