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Proceedings Paper

Controlled plasmonic cell fusion and its implications on the actin cytoskeleton (Conference Presentation)
Author(s): Julia Belansky; Limor Minai; Dvir Yelin

Paper Abstract

Cell fusion is an important process that occurs during normal development, as well as during cancer growth and metastasis. Using specific gold nanoparticles and intense femtosecond laser pulses to induce plasmonic cell fusion, we study the reorganization of the actin network within the fused cells, network that is known to be highly involved in epithelial-mesenchymal transitions. Time-lapse confocal microscopy of the fused cells showed large-scale actin networks within the giant hybrid cells, with unique reorganization dynamics that preserve the original filament orientation of original cells.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11270, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX, 112700A (9 March 2020); doi: 10.1117/12.2544830
Show Author Affiliations
Julia Belansky, Technion-Israel Institute of Technology (Israel)
Limor Minai, Technion-Israel Institute of Technology (Israel)
Dvir Yelin, Technion-Israel Institute of Technology (Israel)

Published in SPIE Proceedings Vol. 11270:
Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XX
Peter R. Herman; Michel Meunier; Roberto Osellame, Editor(s)

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