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Proceedings Paper

Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization
Author(s): Shun Takeda; Hiroshi Kumagai; Mineyuki Hattori
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Paper Abstract

In recent years, MRI using a rare gas has attracted attention. Rare gas MRI can perform imaging of lungs with few protons and can also evaluate gas dynamics and hemodynamics. Attempts have been made to enhance the signal intensity by hyperpolarizing nuclear spins to obtain NMR signals from the gas. This hyperpolarization technology is also expected to be effective when combined with low-field MRI including permanent magnet type. In this study, a xenon (129Xe) hyperpolarization system using a 795nm laser was constructed and evaluated using a 0.3T NMR system. As a result, it was shown that the NMR signal intensity from 129Xe can be enhanced 1.5 times with a polarization of 30 minutes.

Paper Details

Date Published: 17 February 2020
PDF: 5 pages
Proc. SPIE 11243, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII, 112431W (17 February 2020); doi: 10.1117/12.2544572
Show Author Affiliations
Shun Takeda, Kitasato Univ. (Japan)
Hiroshi Kumagai, Kitasato Univ. (Japan)
Mineyuki Hattori, National Institute of Advanced Industrial Science and Technology (Japan)

Published in SPIE Proceedings Vol. 11243:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII
Daniel L. Farkas; Attila Tarnok, Editor(s)

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