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Proceedings Paper

Multifunctional optical coherence tomography for endoscopic in-vivo imaging of lungs periphery in asthma patients (Conference Presentation)

Paper Abstract

We present a motorized distal scanning endoscope with an outer diameter of 1.35 mm and 52 fps rotation speed for in vivo imaging in the peripheral airways of lungs. Three lung segments of an asthma patient pre and post bronchial thermoplasty (BT) treatment were imaged. Optical coherence tomography (OCT) intensity images, attenuation coefficient (AC) images and polarization sensitive OCT (PS-OCT) images showing both birefringence, optic axis uniformity (OAxU) and optic axis (OA) orientation were extracted from the acquired data. PS-OCT endoscopy visualized airway smooth muscle layer thickness and location pre and post BT treatment as means to predict its effectiveness.

Paper Details

Date Published: 6 March 2020
Proc. SPIE 11214, Endoscopic Microscopy XV, 112140D (6 March 2020); doi: 10.1117/12.2544318
Show Author Affiliations
Margherita Vaselli, Vrije Univ. Amsterdam (Netherlands)
Fabio Feroldi, Vrije Univ. Amsterdam (Netherlands)
Joy Willemse, Vrije Univ. Amsterdam (Netherlands)
Valentina Davidoiu, Vrije Univ. Amsterdam (Netherlands)
Maximilian G. O. Graefe, Vrije Univ. Amsterdam (Netherlands)
Dirck van Iperen, Vrije Univ. Amsterdam (Netherlands)
Johannes F. de Boer, Vrije Univ. Amsterdam (Netherlands)

Published in SPIE Proceedings Vol. 11214:
Endoscopic Microscopy XV
Guillermo J. Tearney M.D.; Thomas D. Wang; Melissa J. Suter, Editor(s)

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