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Proceedings Paper

Adaptive glasses-assisted Full-Field OCT for SNR enhanced 3D high-resolution retinal imaging (Conference Presentation)

Paper Abstract

To achieve 3D high-cellular resolution, a great effort, in the past years, was made to develop Adaptive Optics (AO)-OCT systems. However, such systems require quite complex, expensive and cumbersome hardware, making clinical transfer challenging. Recently, we demonstrated that the use of spatially incoherent illumination in Time-Domain Full-Field (FF)-OCT offers a valuable advantage: the lateral resolution is almost insensitive to ocular aberrations that only affect the FF-OCT signal level. We took advantage of this property to image in-vivo photoreceptor mosaic without using an AO technique. Nevertheless, the FF-OCT technique was still facing some challenges in providing consistent and reproducible images, mainly due to axial eye motion and reduced signal level. Here, we present the Adaptive Glasses-assisted FF-OCT, where an adaptive lens is placed just in front of the eye, like spectacles, enabling correction of the first 10 Zernike polynomials, increasing the FF-OCT signal level.

Paper Details

Date Published: 9 March 2020
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Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112281O (9 March 2020); doi: 10.1117/12.2544277
Show Author Affiliations
Pedro Mecê, Institut Langevin Ondes et Images (France)
Jules Scholler, Institut Langevin Ondes et Images (France)
Kassandra Groux, Institut Langevin Ondes et Images (France)
Mathias Fink, Institut Langevin Ondes et Images (France)
Kate Grieve, Institut de la Vision, Ctr. Hospitalier National d'Opthalmologie des Quinze-Vingts (France)
Claude Boccara, Institut Langevin Ondes et Images (France)


Published in SPIE Proceedings Vol. 11228:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV
Joseph A. Izatt; James G. Fujimoto, Editor(s)

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