Share Email Print
cover

Proceedings Paper

First biopotential recordings from a liquid crystal optrode
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

One of the goals of the Neural Engineering System Design (NESD) program in the United States and of similar programs around the world is to develop an interface able to read from one million neurons in parallel. This is well beyond the capabilities of traditional multi-electrode arrays (MEAs), which are inherently limited in both spatial resolution and number of channels, due to issues with power dissipation and wiring.1, 2 To overcome these roadblocks our group has proposed a novel optrode array that measures electrical activity and uses light for both signal transduction and transmission, thus decoupling the bio-potentials from the signal acquisition circuitry.3 The technology relies on the sensitivity of a particular class of liquid crystals (LCs) to small electric fields and is analogous to a LC display, where the intensity of each pixel (optrode, in our case) is controlled by the electrical activity of the biological tissue. Here, we present the first use of such a transduction mechanism to record from cardiac tissue and investigate stimulus artifact suppression in rabbit sciatic nerve. Our results pave the way to the development of high-density high-channel-count optrode arrays for electrophysiology studies and brain-machine interfaces.

Paper Details

Date Published: 17 February 2020
PDF: 4 pages
Proc. SPIE 11225, Clinical and Translational Neurophotonics 2020, 1122505 (17 February 2020); doi: 10.1117/12.2544087
Show Author Affiliations
Leonardo Silvestri, The Univ. of New South Wales (Australia)
Amr Al Abed, The Univ. of New South Wales (Australia)
Emilie C. M. Revol, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Josiah Firth, The Univ. of New South Wales (Australia)
Yuan Wei, The Univ. of New South Wales (Australia)
Han Wang, The Univ. of New South Wales (Australia)
Nathalie Gouailhardou, The Univ. of New South Wales (Australia)
Torsten Lehmann, The Univ. of New South Wales (Australia)
Nigel H. Lovell, The Univ. of New South Wales (Australia)
François Ladouceur, The Univ. of New South Wales (Australia)


Published in SPIE Proceedings Vol. 11225:
Clinical and Translational Neurophotonics 2020
Steen J. Madsen; Victor X. D. Yang; Nitish V. Thakor, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray