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Proceedings Paper

Ultra-high-speed wide-field photoacoustic microscopy using a polygon mirror scanner (Conference Presentation)

Paper Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) has become a popular tool in small-animal studies. However, previous OR-PAM techniques variously lacked a high imaging speed, a high spatial resolution, and/or a large field of view. Here we report a high-speed OR-PAM system using an innovative water-immersible polygon-mirror scanner, which has achieved a cross-sectional frame rate of as high as 1200 Hz over a 12-mm scanning range. Using this polygon-scanner-based OR-PAM system, we have performed various studies on mouse models with stroke and cardiac arrests. We expect that the new OR-PAM system will become a powerful tool for imaging hemodynamics and neuronal functions.

Paper Details

Date Published: 6 March 2020
Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112401W (6 March 2020); doi: 10.1117/12.2543914
Show Author Affiliations
Junjie Yao, Duke Univ. (United States)
Bangxin Lan, Duke Univ. (United States)
Wei Liu, Duke Univ. (United States)
Qifa Zhou, The Univ. of Southern California (United States)
Jun Zou, Texas A&M Univ. (United States)
Ulrike Hoffmann, Duke Univ. (United States)
Wei Yang, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 11240:
Photons Plus Ultrasound: Imaging and Sensing 2020
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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