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Proceedings Paper

Free-electron-mediated effects of single femtosecond pulses and pulse series in the (irradiance/fluence) parameter space (Conference Presentation)

Paper Abstract

Laser-induced plasma generation by single and multiple femtosecond laser pulses is used surgically and constitutes a source of photodamage in nonlinear microscopy. The irradiance threshold at which transient vapor bubbles in water are produced is 20x higher than the irradiance used for nonlinear microscopy. However, photodamage in multiphoton microscopy already starts, when the irradiance is 1.5x above autofluorescence imaging. Thus, there is a huge realm of low-density plasma effects between the multi-pulse damage threshold and the single-pulse surgical regime, and the talk will provide a systematic overview over laser applications and the irradiance and radiant exposure dependence of these effects.

Paper Details

Date Published: 9 March 2020
Proc. SPIE 11238, Optical Interactions with Tissue and Cells XXXI, 1123803 (9 March 2020); doi: 10.1117/12.2543680
Show Author Affiliations
Norbert Linz, Univ. zu Lübeck (Germany)
Xiao-Xuan Liang, Univ. zu Lübeck (Germany)
Sebastian Freidank, Univ. zu Lübeck (Germany)
Alfred Vogel, Univ. zu Lübeck (Germany)

Published in SPIE Proceedings Vol. 11238:
Optical Interactions with Tissue and Cells XXXI
Bennett L. Ibey; Norbert Linz, Editor(s)

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