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Proceedings Paper

Robust 4D wavefront control through coherent fiber bundles for lensless endoscopy and optical tweezing (Conference Presentation)
Author(s): Elias Scharf; Robert Kuschmierz; Jürgen Czarske

Paper Abstract

We present a fast holographic endoscope with needle footprint. Robustness versus bending is achieved by a single sided self-calibration of the fiber bundle. Incorporating an adaptive lens and 2-axis galvo scanner allows 3D scans with one Mega voxel per second. While the 3D imaging is demonstrated at 3µm fluorescent beads, we also demonstrate the applicability in 2-axis cell rotators by precisely rotating two foci with an angle uncertainty below 1°. For the future, we expect this approach will lead us to create tools for deeper tissue imaging and cell manipulation.

Paper Details

Date Published: 11 March 2020
Proc. SPIE 11248, Adaptive Optics and Wavefront Control for Biological Systems VI, 112480T (11 March 2020); doi: 10.1117/12.2543213
Show Author Affiliations
Elias Scharf, TU Dresden (Germany)
Robert Kuschmierz, TU Dresden (Germany)
Jürgen Czarske, TU Dresden (Germany)

Published in SPIE Proceedings Vol. 11248:
Adaptive Optics and Wavefront Control for Biological Systems VI
Thomas G. Bifano; Sylvain Gigan; Na Ji, Editor(s)

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