A novel lipid sensitive OCT setup is presented, using light source with a central wavelength of 1280 nm and a spectral tuning range of 201 nm. A cholesterol plaque located in the aorta was imaged post mortem. Different spectral bands were chosen in post processing. Analyzing the signal attenuation of the different spectral bands enables us to see a clear difference between the lipid absorption in the plaque between the bands. In the normal tissue no clear separation of the signal attenuation can be found. This enables us to visualize the plaque on a three dimensional level.

Date Published: 9 March 2020
PDF
Proc. SPIE 11215, Diagnostic and Therapeutic Applications of Light in Cardiology 2020, 1121504 (9 March 2020); doi: 10.1117/12.2543158

Published in SPIE Proceedings Vol. 11215:
Diagnostic and Therapeutic Applications of Light in Cardiology 2020
Kenton W. Gregory M.D.; Laura Marcu, Editor(s)