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Proceedings Paper

Stimulated Raman scattering imaging by an achromatic metalens (Conference Presentation)
Author(s): Peng Lin; Wei Ting Chen; Kerolos M. A. Yousef; Alexander Y. Zhu; Justin Marchioni; Jiayinzi Wu; Federico Capasso; Ji-Xin Cheng

Paper Abstract

Miniature stimulated Raman scattering (SRS) imaging systems such as an SRS handheld probe and endoscope will enable label-free in vivo optical-biopsy for human patient investigation. Towards the miniature system, the challenge remains at the design and fabrication of such an achromatic micro-objective with low optical aberrations. Recent advances in achromatic metalenses with diffraction-limited performance open the opportunity to tackle the challenge. Here, we demonstrate the first proof-of-concept of metalens-enabled SRS imaging. The metalenses hold great potentials for developing endoscopic SRS and nonlinear imaging system for future clinical applications.

Paper Details

Date Published: 10 March 2020
Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112520I (10 March 2020); doi: 10.1117/12.2542966
Show Author Affiliations
Peng Lin, Boston Univ. (United States)
Wei Ting Chen, Harvard Univ. (United States)
Kerolos M. A. Yousef, College of Biotechnology, MISR Univ. for Science and Technology (Egypt)
Alexander Y. Zhu, Harvard Univ. (United States)
Justin Marchioni, Univ. of Waterloo (Canada)
Jiayinzi Wu, Boston Univ. (United States)
Federico Capasso, Harvard Univ. (United States)
Ji-Xin Cheng, Boston Univ. (United States)

Published in SPIE Proceedings Vol. 11252:
Advanced Chemical Microscopy for Life Science and Translational Medicine
Ji-Xin Cheng; Wei Min; Garth J. Simpson, Editor(s)

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