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Proceedings Paper

Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging (Conference Presentation)
Author(s): Yan Li; Zhikai Zhu; Jason J. Chen; Joseph C. Jing; Zhongping Chen

Paper Abstract

Endoscopic optical coherence tomography (OCT) and near-infrared (NIR) fluorescence imaging system was developed for characterization of colorectal cancer (CRC). NIR fluorescence is able to highlight the cancer-suspected area based on significant change of tumor vascular density and morphology. Co-registered OCT images has the capability of visualizing subsurface tissue layer architecture, so the suspected regions can be further investigated by the altered light scattering resulted from the morphological abnormality. The imaging result from in vivo rat experiment has demonstrated the enhanced capability of identification and classification of CRC compared to using any of these technologies alone, thus has the potential to provide a new clinical tool to advance gastroenterology practice.

Paper Details

Date Published: 9 March 2020
PDF
Proc. SPIE 11232, Multimodal Biomedical Imaging XV, 112320F (9 March 2020); doi: 10.1117/12.2542964
Show Author Affiliations
Yan Li, Univ. of California, Irvine (United States)
Zhikai Zhu, Univ. of California, Irvine (United States)
Jason J. Chen, Univ. of California, Irvine (United States)
Joseph C. Jing, Univ. of California, Irvine (United States)
Zhongping Chen, Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 11232:
Multimodal Biomedical Imaging XV
Fred S. Azar; Xavier Intes; Qianqian Fang, Editor(s)

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