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Proceedings Paper

Dual-mode endoscopic probe combining OCT and autofluorescence imaging for inner ear hearing loss diagnosis and therapy guidance (Conference Presentation)
Author(s): Jesung Park; Jeffrey T. Cheng; Daniel Lee; Jeffrey Holt; Hannah Goldberg; Gopi N. Maguluri; John Grimble; Nicusor V. Iftimia

Paper Abstract

This study presents a novel technology for in vivo cochlear imaging in sensorineural hearing loss (SNHL). SNHL is the most common type of permanent hearing loss and is associated with damaged hair cells of the cochlea. State of the art clinical imaging does not have sufficient resolution to show inner ear microstructure. We are developing and testing a dual-modal endoscopic instrument that combines optical coherence tomography (OCT) and autofluorescence imaging (AFI) for dynamic cochlear imaging. If successful, this approach will improve our understanding of the cellular basis of SNHL and enable the development of targeted therapies for inner ear disorders.

Paper Details

Date Published: 6 March 2020
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Proc. SPIE 11213, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2020, 1121303 (6 March 2020); doi: 10.1117/12.2542678
Show Author Affiliations
Jesung Park, Physical Sciences Inc. (United States)
Jeffrey T. Cheng, Massachusetts Eye and Ear (United States)
Daniel Lee, Massachusetts Eye and Ear (United States)
Jeffrey Holt, Boston Children's Hospital (United States)
Hannah Goldberg, Boston Children's Hospital (United States)
Gopi N. Maguluri, Physical Sciences Inc. (United States)
John Grimble, Physical Sciences Inc. (United States)
Nicusor V. Iftimia, Physical Sciences Inc. (United States)


Published in SPIE Proceedings Vol. 11213:
Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2020
Brian J. F. Wong M.D.; Justus F. Ilgner M.D., Editor(s)

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