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Proceedings Paper

A regularized quantitative ultrasound method for simultaneous calculation of backscatter and attenuation coefficients
Author(s): Stefano E. Romero; Andres Coila; Roberto J. Lavarello
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Paper Abstract

Quantitative ultrasound has shown potential of improving medical diagnosis. In this work, a regularized power law (RPL) for the joint estimation of backscatter coefficient (BSC) and attenuation coefficient (AC) parameters was derived and tested with simulated phantoms and in vivo. For the RPL method, a total variation regularization term regarding the BSC and AC parameters were used. The results were compared with ground truth simulated values. An improvement of precision can be appreciated without compromising the accuracy by factor of 80% and 54% according to bias and coefficient of variation, respectively. The in vivo experiments showed comparable results of the algorithm with the literature (i.e. fibroadenoma:1.90 ± 0.31dB.cm−1 .MHz−1 , normal tissue: 0.62 ± 0.20dB.cm−1 .MHz−1 ). The results suggest the RPL method has the potential to accurately and precisely estimating BSCs and ACs.

Paper Details

Date Published: 3 January 2020
PDF: 11 pages
Proc. SPIE 11330, 15th International Symposium on Medical Information Processing and Analysis, 113300T (3 January 2020); doi: 10.1117/12.2542460
Show Author Affiliations
Stefano E. Romero, Pontificia Univ. Católica del Perú (Peru)
Andres Coila, Univ. of Illinois at Urbana-Champaign (United States)
Roberto J. Lavarello, Pontificia Univ. Católica del Perú (Peru)


Published in SPIE Proceedings Vol. 11330:
15th International Symposium on Medical Information Processing and Analysis
Eduardo Romero; Natasha Lepore; Jorge Brieva, Editor(s)

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