Development of optically active nanomaterials for pH sensing at biological environments can offer many advantages for biomedical examinations and drug delivery applications. Raman spectroscopy, a rapid and low intrusive optical technique, has been widely used in biological studies. Since pH is an important variable in many pathological and physiological pathways, nanoscale Raman pH probes can expand opportunities for pH sensing and controlling at biological interfaces. In this study, Raman spectra of a pH responsive selfassembled mesophase in water was investigated upon varying the pH of the solution. Raman peaks of the mesophase can be addressed as pH dependent optical output, enabling the material to be used as a nanoplatform for Raman pH sensing.

Date Published: 21 February 2020
PDF: 5 pages
Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 1125410 (21 February 2020); doi: 10.1117/12.2542452

Published in SPIE Proceedings Vol. 11254:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII
Dror Fixler; Ewa M. Goldys, Editor(s)