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Proceedings Paper

Intracellular Doppler spectroscopy for label-free functional imaging of living tissue (Conference Presentation)
Author(s): David D. Nolte

Paper Abstract

Motions inside living tissues are ubiquitous signatures of the active processes involved in the maintenance of cellular function and health. An innovative label-free non-invasive imaging technology called Biodynamic Imaging (BDI), based on low-coherence interferometry and digital holography, captures intracellular dynamics through ultra-low-frequency Doppler spectra encoding a broad range of cellular and subcellular motions. Clinical trials of BDI assessing patient response to therapy are underway in human ovarian, esophageal and breast cancers.

Paper Details

Date Published: 10 March 2020
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Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125106 (10 March 2020); doi: 10.1117/12.2542443
Show Author Affiliations
David D. Nolte, Purdue Univ. (United States)


Published in SPIE Proceedings Vol. 11251:
Label-free Biomedical Imaging and Sensing (LBIS) 2020
Natan T. Shaked; Oliver Hayden, Editor(s)

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