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Proceedings Paper

Terahertz spectrometer based on widely tunable injection-seeded terahertz parametric generation and detection for identifying pharmaceutical materials
Author(s): M. Mohara; K. Shimura; K. Aiko; T. Ono
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Paper Abstract

Terahertz (THz) spectroscopy is expected as a new technique for nondestructive inspection of pharmaceutical tablets, because THz waves pass through a wide variety of pharmaceutical materials. We have been developing a frequency domain THz spectrometer with an injection-seeded THz parametric generation (is-TPG) technique. In this study, the frequency range of the spectrometer was successfully expanded to 0.9-4.2 THz by generating widely tunable THz waves by shifting a nonlinear crystal to balance gain and absorption of the THz waves in the crystal, and detecting the THz waves with an angle-compensation method that utilized the dispersion of the crystal. Absorption spectra of the crystal polymorphs of carbamazepine forms I and III were obtained with the THz spectrometer, and these polymorphs were identified by specific absorption peaks related to their solid state.

Paper Details

Date Published: 2 March 2020
PDF: 6 pages
Proc. SPIE 11279, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications XIII, 112790X (2 March 2020); doi: 10.1117/12.2541794
Show Author Affiliations
M. Mohara, Hitachi High-Technologies Corp. (Japan)
K. Shimura, Hitachi High-Technologies Corp. (Japan)
K. Aiko, Hitachi High-Technologies Corp. (Japan)
T. Ono, Hitachi High-Technologies Corp. (Japan)

Published in SPIE Proceedings Vol. 11279:
Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications XIII
Laurence P. Sadwick; Tianxin Yang, Editor(s)

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