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Proceedings Paper

Video-rate multi-exposure laser speckle contrast imaging for real-time microcirculation blood flow assessment in skin (Conference Presentation)
Author(s): Martin Hultman; Ingemar Fredriksson; Marcus Larsson; Tomas Strömberg

Paper Abstract

This talk highlights a novel instrument for real-time video-rate imaging of microcirculation blood flow. The instrument utilizes multi-exposure laser speckle contrast imaging (MELSCI) with a high-speed camera, custom integrated electronics, and machine learning for massive computational bandwidth. This instrument enables, for the first time, continuous in vivo imaging of blood flow at frame rates sufficiently high to track dynamic changes, with perfusion estimates strongly correlated with that of laser Doppler flowmetry (LDF). This is an important step enabling a better understanding of the role of the microcirculation in several cardiovascular diseases. A pilot study on healthy subjects is presented.

Paper Details

Date Published: 6 March 2020
Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 112110Y (6 March 2020); doi: 10.1117/12.2541659
Show Author Affiliations
Martin Hultman, Linköping Univ. (Sweden)
Ingemar Fredriksson, Linköping Univ. (Sweden)
Perimed AB (Sweden)
Marcus Larsson, Linköping Univ. (Sweden)
Tomas Strömberg, Linköping Univ. (Sweden)

Published in SPIE Proceedings Vol. 11211:
Photonics in Dermatology and Plastic Surgery 2020
Bernard Choi; Haishan Zeng, Editor(s)

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