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Proceedings Paper

Clinical applicability of in vivo harmonic generation microscopy for the diagnosis and grading of actinic keratosis (Conference Presentation)
Author(s): Chi-Kuang Sun; Yi Pan; Pei-Che Wu; Sheng-Tse Chen; Yi-Hua Liao

Paper Abstract

Actinic keratosis (AK) is a common cutaneous neoplasm resulting from severe solar damage. Noninvasive diagnosis and grading of AK are important not just because of AK’s precancerous nature, but also due to the frequent presence of multiple AKs. Here we study the clinical applicability of in vivo harmonic generation microscopy (HGM) for the grading, diagnosis, and treatment assessment of AKs. As a result, 100% agreement on diagnosis and grading outcomes between HGM and traditional histopathology were obtained. Our study indicates the superior capability of in vivo HGM for diagnosis, grading, and treatment assessment of AKs.

Paper Details

Date Published: 6 March 2020
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Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 1121107 (6 March 2020); doi: 10.1117/12.2541484
Show Author Affiliations
Chi-Kuang Sun, National Taiwan Univ. (Taiwan)
Yi Pan, National Taiwan Univ. (Taiwan)
Pei-Che Wu, National Taiwan Univ. (Taiwan)
Sheng-Tse Chen, National Taiwan Univ. (Taiwan)
Yi-Hua Liao, National Taiwan Univ. Hospital (Taiwan)


Published in SPIE Proceedings Vol. 11211:
Photonics in Dermatology and Plastic Surgery 2020
Bernard Choi; Haishan Zeng, Editor(s)

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