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Chemical sensing based on silk coated exposed-core fibers
Author(s): Lu Peng; Asma Khalid; Stephen C. Warren-Smith; Azim Arman; Erik P. Schartner; Georgina Maree Sylvia; Mark R. Hutchinson; Heike Ebendorff-Heidepriem; Robert A. McLaughlin; Brant C. Gibson; Jiawen Li
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Paper Abstract

We demonstrate in-vivo chemical sensing using silk-coated exposed-core microstructured optical fibers (ECFs). The ECF provides advantages in sensitivity due to the direct access of the fiber core to the surrounding environment with integrated measurement along the entire fiber length, rather than simply the fiber tip as is common in other probes. The silk coating provides an encapsulation of the sensor molecules, and is well known as a biocompatible material. This deployable fiber sensor is fabricated with simple splicing and coating techniques, making it practical to be used in a range of biomedical sensing applications, which we demonstrate through pH sensing in a mouse model.

Paper Details

Date Published: 30 December 2019
PDF: 2 pages
Proc. SPIE 11202, Biophotonics Australasia 2019, 112020G (30 December 2019); doi: 10.1117/12.2541320
Show Author Affiliations
Lu Peng, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Asma Khalid, ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
RMIT Univ. (Australia)
Stephen C. Warren-Smith, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Azim Arman, ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Adelaide Medical School (Australia)
Erik P. Schartner, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Georgina Maree Sylvia, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Mark R. Hutchinson, ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
The Univ. of Adelaide (Australia)
Heike Ebendorff-Heidepriem, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Robert A. McLaughlin, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Adelaide Medical School (Australia)
Brant C. Gibson, ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
RMIT Univ. (Australia)
Jiawen Li, The Univ. of Adelaide (Australia)
ARC Ctr. of Excellence for Nanoscale Biophotonics (Australia)
Adelaide Medical School (Australia)


Published in SPIE Proceedings Vol. 11202:
Biophotonics Australasia 2019
Ewa M. Goldys; Brant C. Gibson, Editor(s)

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