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Proceedings Paper

Interrogation of photonic biosensors using optical frequency combs
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Paper Abstract

In this contribution, we show how the stability and ease-of-use of an integrated interferometric photonic biosensor platform can be enhanced using optical frequency combs, without any necessary changes to the sensor chip design. We show that if the comb line spacing of the optical frequency comb is adjusted to be at 120° intervals of the periodic spectral response of the used Mach-Zehnder interferometer and the transmission power values of the three comb lines are recorded over time, it is possible to extract the interferometer phase linearly and continuously for every sample point. This measurement approach provides an accurate phase measurement and is independent of the interferometer bias. Furthermore, it is robust against intensity fluctuations which are common to all three used comb lines. Our demonstration uses a simple silicon photonic interferometric refractive index sensor, and we show that the benefits of our approach can be achieved without degrading the lower limit of detection of 3.70×10-7 RIU of our sensor platform. Our technique can be applied to any interferometric sensor and only requires a single input and single output and does not need any special couplers. This technique offers a drop-in replacement to the commonly used single wavelength phase measurement.

Paper Details

Date Published: 30 December 2019
PDF: 2 pages
Proc. SPIE 11202, Biophotonics Australasia 2019, 112020B (30 December 2019); doi: 10.1117/12.2541248
Show Author Affiliations
Markus Knoerzer, RMIT Univ. (Australia)
Crispin Szydzik, RMIT Univ. (Australia)
Monash Univ. (Australia)
Guanghui Ren, RMIT Univ. (Australia)
Cesar S. Huertas, RMIT Univ. (Australia)
Sonya Palmer, RMIT Univ. (Australia)
Phuong Tang, RMIT Univ. (Australia)
Thach G. Nguyen, RMIT Univ. (Australia)
Lam Bui, Central Queensland Univ. (Australia)
Andreas Boes, RMIT Univ. (Australia)
Arnan Mitchell, RMIT Univ. (Australia)

Published in SPIE Proceedings Vol. 11202:
Biophotonics Australasia 2019
Ewa M. Goldys; Brant C. Gibson, Editor(s)

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