Share Email Print
cover

Proceedings Paper

Bright upconversion nanoparticles under light-emitting diode excitation
Author(s): Yueying Cao; Xianlin Zheng; James A. Piper; Nicolle H. Packer; Yiqing Lu
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infrared (NIR) excitation to visible and ultraviolet emission via stepwise multiphoton processes. They offer unique advantages (e.g. sharp emission bands, superb photostability and long lifetimes1) compared to conventional dyes and quantum dots, enabling advanced detection and imaging for biologically important molecules. However, their application to live cells and small animals has been practically limited due to the potential damage under high-power laser illumination, as well as concerns for life scientists who do not necessary possess sufficient knowledge and experience in laser safety. Therefore, we have been exploring new strategies to develop UCNPs that are capable of excitation by incoherent sources such as light-emitting diodes (LEDs), in particular via increased number of sensitizer ions and coating of inert shells.

Paper Details

Date Published: 30 December 2019
PDF: 2 pages
Proc. SPIE 11202, Biophotonics Australasia 2019, 112021P (30 December 2019); doi: 10.1117/12.2541246
Show Author Affiliations
Yueying Cao, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
Macquarie Univ. (Australia)
Xianlin Zheng, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
Macquarie Univ. (Australia)
James A. Piper, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
Macquarie Univ. (Australia)
Nicolle H. Packer, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
Macquarie Univ. (Australia)
Yiqing Lu, ARC Ctr. of Excellence for Nanoscale BioPhotonics (Australia)
Macquarie Univ. (Australia)


Published in SPIE Proceedings Vol. 11202:
Biophotonics Australasia 2019
Ewa M. Goldys; Brant C. Gibson, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray