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Higher order correlation scaling for optical super-resolution imaging: implications of photon counting and quantum imaging for practical nanoscopy
Author(s): Joshua Gray; Josef G. Worboys; Daniel W. Drumm; Shuo Li; Andrew D. Greentree
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Paper Abstract

Techniques of optical superresolution imaging are vital for uncovering the complex dynamics of biochemistry in cellular environments. However the practical resolution for superresolution imaging is limited by the increased photon budget for superresolution, compared with conventional microscopy. For this reason it is important to determine the optimal methods for analysing all of the incoming information. Most approaches to microscopy use only the wave-like properties of light, but the particle-like nature of light provides extra information that is normally inaccessible and can be used to increase imaging resolution. Here we theoretically study the localisation of quantum emitters using higher-order quantum correlation functions to understand the resolution that is practically achievable for bio-imaging tasks. We show explicit imaging results for varying number of emitters as a function of correlation order to illustrate the necessary tradeoffs between imaging resolution and acquisition time.

Paper Details

Date Published: 30 December 2019
PDF: 2 pages
Proc. SPIE 11202, Biophotonics Australasia 2019, 112021M (30 December 2019); doi: 10.1117/12.2541208
Show Author Affiliations
Joshua Gray, RMIT Univ. (Australia)
Josef G. Worboys, RMIT Univ. (Australia)
Daniel W. Drumm, RMIT Univ. (Australia)
Shuo Li, RMIT Univ. (Australia)
Andrew D. Greentree, RMIT Univ. (Australia)


Published in SPIE Proceedings Vol. 11202:
Biophotonics Australasia 2019
Ewa M. Goldys; Brant C. Gibson, Editor(s)

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