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Combined optical and electrochemical analysis of protein binding with ITO-coated lossy-mode resonance sensor
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Paper Abstract

This work discuses indium tin oxide (ITO) coated optical fiber lossy-mode resonance (LMR) sensor working in an electrochemical setup for monitoring of protein binding to the sensor’s surface. The binding mechanism has been observed simultaneously in optical and electrochemical domain. The combined measurement was enabled by the electrically conductive ITO overlay. In the experiment, biotin molecules have been used to test the collective optical and electrochemical setup and to illustrate the binding effect. It has been shown that the effect is observed in the investigated domains at applied potential, and the qualitative comparison shows high resemblance of the outcome.

Paper Details

Date Published: 28 August 2019
PDF: 4 pages
Proc. SPIE 11199, Seventh European Workshop on Optical Fibre Sensors, 111991E (28 August 2019); doi: 10.1117/12.2540849
Show Author Affiliations
Marcin Koba, Warsaw Univ. of Technology (Poland)
National Institute of Telecommunications (Poland)
Dariusz Burnat, Warsaw Univ. of Technology (Poland)
Katarzyna Szot-Karpińska, Institute of Physical Chemistry (Poland)
Petr Sezemsky, Univ. of South Bohemia (Czech Republic)
Vitezslav Stranak, Univ. of South Bohemia (Czech Republic)
Robert Bogdanowicz, Gdansk Univ. of Technology (Poland)
Joanna Niedziółka-Jönsson, Institute of Physical Chemistry (Poland)
Mateusz Śmietana, Warsaw Univ. of Technology (Poland)


Published in SPIE Proceedings Vol. 11199:
Seventh European Workshop on Optical Fibre Sensors
Kyriacos Kalli; Sinead O. O'Keeffe; Gilberto Brambilla, Editor(s)

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