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Tissue diagnosis using nanoscale morphological markers extracted from quantitative phase images
Author(s): Masanori Takabayashi; Hassaan Majeed; Andre Kajdacsy-Balla; Gabriel Popescu
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Paper Abstract

The intrinsic markers of nanoscale morphological alteration in fixed tissue biopsy referred to as disorder strength and local correlation length, which can be easily and time-efficiently obtained from quantitative phase images, are introduced. After presenting how to extract these markers from quantitative phase images obtained by highly sensitive quantitative phase imaging system, spatial light interference microscopy (SLIM), we demonstrate the effectiveness of these markers for diagnosis of benign and malignant breast tissues.

Paper Details

Date Published: 19 November 2019
PDF: 10 pages
Proc. SPIE 11185, Optical Design and Testing IX, 111850B (19 November 2019); doi: 10.1117/12.2538728
Show Author Affiliations
Masanori Takabayashi, Kyushu Institute of Technology (Japan)
Hassaan Majeed, Univ. of Illinois at Urbana-Champaign (United States)
Andre Kajdacsy-Balla, Univ. of Illinois at Chicago (United States)
Gabriel Popescu, Univ. of Illinois at Urbana-Champaign (United States)


Published in SPIE Proceedings Vol. 11185:
Optical Design and Testing IX
Yongtian Wang; Pablo Benítez; Osamu Matoba, Editor(s)

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