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Proceedings Paper

Research progress of coronary artery calcification based on optical coherence tomography
Author(s): Na Qin; Jingbo Wang; Danni Liu; Yana Liu; Lin Huang; Qin Li
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Paper Abstract

Optical coherence tomography (OCT) is a new medical imaging technology that developed at the end of the 20th century after X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and intravascular ultrasound (IVUS). It is called “optical biopsy” technology with the advantages of no radiation, simple structure and high resolution that can reach ten times that of IVUS. However, OCT also has the disadvantage of insufficient depth of detection that only a few millimeters and imaging speed. Even so, OCT can be used in combination with microscopes, medical catheters and endoscopes; therefore, it has broad application prospects in the field of biomedicine. The OCT system is simple in structure, mainly Michelson interferometer. Using the principle of optical coherence imaging, it detects the back-reflecting or scattering signals of incident light at different depths of biological tissue to obtain the surface and subsurface imaging of transparent or opaque substances. The combination of OCT and endoscopy extends the use of OCT to the diagnosis of cardiovascular diseases, which is called intravascular optical coherence tomography (IVOCT). It enables rapid visualization of microscopic images of vascular cross sections and is a powerful tool for clinical detection of coronary atherosclerosis, in which coronary artery calcification is a common problem in the clinic and is closely related to cardiovascular diseases. This review will briefly introduce the principle of OCT technology and its application in cardiovascular diseases, and focus on the research progress of detection of coronary artery calcification based on OCT technology.

Paper Details

Date Published: 19 November 2019
PDF: 8 pages
Proc. SPIE 11186, Advanced Optical Imaging Technologies II, 111861D (19 November 2019); doi: 10.1117/12.2537772
Show Author Affiliations
Na Qin, Beijing Institute of Technology (China)
Jingbo Wang, Beijing Institute of Technology (China)
North China Univ. of Science and Technology (China)
Danni Liu, Beijing Institute of Technology (China)
Yana Liu, Beijing Institute of Technology (China)
Lin Huang, Beijing Institute of Technology (China)
Qin Li, Beijing Institute of Technology (China)

Published in SPIE Proceedings Vol. 11186:
Advanced Optical Imaging Technologies II
Xiao-Cong Yuan; P. Scott Carney; Kebin Shi; Michael G. Somekh, Editor(s)

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