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Proceedings Paper

Research on ischemia-reperfusion injury of rat kidney using optical coherence tomography
Author(s): Yuhong Fang; Wei Gong; Zheng Huang; Liqin Zheng; Hongxin Lin; Deyuan Yang; Shusen Xie
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Paper Abstract

Renal artery occlusion is an unavoidable process during operations such as nephrectomy, carcinoma resection, kidney transplantation and so on. For minimizing the kidney injury, the optimal renal ischemia time was experimentally investigated. Optical coherence tomography (OCT) is a high resolution imaging modality can non-invasively image biotissue in vivo and in real time. In order to study the relationship between tubular injury and the renal ischemia time, OCT images of Wistar rat kidneys endured various ischemia time were obtained throughout the whole ischemia-reperfusion procedure. The tubular density and the average diameter of uriniferous tubules were considered as biomarker of kidney activity, and the quantitative results well described the degree of kidney injury.

Paper Details

Date Published: 20 November 2019
PDF: 8 pages
Proc. SPIE 11190, Optics in Health Care and Biomedical Optics IX, 1119032 (20 November 2019); doi: 10.1117/12.2537737
Show Author Affiliations
Yuhong Fang, Fujian Normal Univ. (China)
Minnan Normal Univ. (China)
Wei Gong, Fujian Normal Univ. (China)
Zheng Huang, Fujian Normal Univ. (China)
Liqin Zheng, Fujian Normal Univ. (China)
Hongxin Lin, Fujian Normal Univ. (China)
Deyuan Yang, Fujian Normal Univ. (China)
Shusen Xie, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 11190:
Optics in Health Care and Biomedical Optics IX
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang; Dan Zhu, Editor(s)

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