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Proceedings Paper

Axial resolution enhancement in light sheet microscopy using mode modulation
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Paper Abstract

Light sheet fluorescence microscopy (LSFM) is widely used in biological imaging because of its low photobleaching and phototoxicity. The axial resolution of LSFM is determined and also limited by the thickness of the light sheet and the numerical aperture (NA) of the detection objective. We propose a novel method, light sheet modulation fluorescence microscopy (LSMFM) which is able to achieve a promising axial resolution enhancement of light sheet microscopy.

Paper Details

Date Published: 19 November 2019
PDF: 7 pages
Proc. SPIE 11186, Advanced Optical Imaging Technologies II, 1118616 (19 November 2019); doi: 10.1117/12.2537528
Show Author Affiliations
Chengfeng Zhang, Zhejiang Univ. (China)
Yuchen Chen, Zhejiang Univ. (China)
Cuifang Kuang, Zhejiang Univ. (China)
Ningbo Research Institute (China)
Shanxi Univ. (China)
Xu Liu, Zhejiang Univ. (China)
Ningbo Research Institute (China)
Shanxi Univ. (China)


Published in SPIE Proceedings Vol. 11186:
Advanced Optical Imaging Technologies II
Xiao-Cong Yuan; P. Scott Carney; Kebin Shi; Michael G. Somekh, Editor(s)

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