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Nonlinear focal modulation microscopy based on interleaved reconstruction
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Paper Abstract

Nonlinear focal modulation microscopy (NFOMM) is a really simple and effective super-resolution imaging method based on phase modulation with high-intensity illumination, which can extend the effective spatial-frequency bandwidth of the imaging system and achieve a transverse resolution of ~ 60 nm (~λ/10). However, multiple images under different illumination pattern is needed, which result in limited imaging speed. A novel interleaved reconstruction method is proposed to increase the frame rate without any change in the raw data of NFOMM. Since allowing easy integration with confocal microscopes, we anticipate this method will be a useful observation tool in the biological community and other research field.

Paper Details

Date Published: 19 November 2019
PDF: 6 pages
Proc. SPIE 11186, Advanced Optical Imaging Technologies II, 1118611 (19 November 2019); doi: 10.1117/12.2537324
Show Author Affiliations
Yuchen Chen, Zhejiang Univ. (China)
Chengfeng Zhang, Zhejiang Univ. (China)
Cuifang Kuang, Zhejiang Univ. (China)
Ningbo Research Institute (China)
Shanxi Univ. (China)


Published in SPIE Proceedings Vol. 11186:
Advanced Optical Imaging Technologies II
Xiao-Cong Yuan; P. Scott Carney; Kebin Shi; Michael G. Somekh, Editor(s)

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