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Acetylcholinesterase-based biosensing solutions for the detection of organophosphorus pesticides
Author(s): Piotr Walter; Andrzej Pepłowski; Daniel Janczak; Małgorzata Jakubowska
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Paper Abstract

Numerous biosensing configurations have been researched for detection of organophosphorus pesticides in agricultural and household applications. Selectivity for the specific insecticide, sensitivity and low detection limit being the main challenges gives a great potential to targeted enzymatic biosensors. Acetylcholinesterase is being employed in receptors, because organophosphorus pesticides, such as malathion, display inhibitory effect towards it. Proteins within other structures can have decreased activity, be contaminated, denatured or have a diffusion barrier resulting in reduced interaction with the analyte. Choice of the immobilization method for the enzyme may be the most important aspect in the development of electrochemical biosensor. Numerous acetylcholinesterase based biosensing solutions for the detection of organophosphorus pesticides have been reviewed.

Paper Details

Date Published: 6 November 2019
PDF: 9 pages
Proc. SPIE 11176, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2019, 111762V (6 November 2019); doi: 10.1117/12.2536965
Show Author Affiliations
Piotr Walter, Warsaw Univ. of Technology (Poland)
Andrzej Pepłowski, Warsaw Univ. of Technology (Poland)
Daniel Janczak, Warsaw Univ. of Technology (Poland)
Małgorzata Jakubowska, Warsaw Univ. of Technology (Poland)


Published in SPIE Proceedings Vol. 11176:
Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2019
Ryszard S. Romaniuk; Maciej Linczuk, Editor(s)

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