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Proceedings Paper

Label free morphochemical characterization of tissues (Conference Presentation)
Author(s): Francesco Saverio Pavone

Paper Abstract

The recent development and integration of multiple non-linear microscopy techniques in a single instrument has provided new opportunities for integrating morphological and functional information and for correlating the observed molecular and cellular changes with disease behaviour. In particular, multimodal non-linear/linear imaging is able to perform a morpho-chemical quantitative analysis in tumour cells and tissue specimens, providing a high-resolution label-free alternative to both histological and immune-histochemical examination of tissues. In this talk, a brief overview on the non linear and linear laser brain imaging techniques will be displayed for label free detection. Morpho-chemical characterization of tissue will be displayed as an interesting tool for early diagnosis of pathologies: different kind of approaches will be shown for in vivo imaging assisted surgery operation or as tools to support anatomo-pathologists decision.

Paper Details

Date Published: 10 March 2020
Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125115 (10 March 2020); doi: 10.1117/12.2536576
Show Author Affiliations
Francesco Saverio Pavone, LENS - Lab. Europeo di Spettroscopie Non-Lineari (Italy)

Published in SPIE Proceedings Vol. 11251:
Label-free Biomedical Imaging and Sensing (LBIS) 2020
Natan T. Shaked; Oliver Hayden, Editor(s)

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