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Proceedings Paper

Scattering assisted imaging (Conference Presentation)
Author(s): Marco Leonetti; Alfonso Grimaldi; Silvia Ghirga; Giancarlo Ruocco; Giuseppe Antonacci

Paper Abstract

Standard imaging systems provide a spatial resolution that is ultimately dictated by the numerical aperture. In biological tissues, the resolution degraded by scattering which limits the imaging at a depth. Here, we exploit the properties of speckle patterns embedded into a strongly scattering matrix to illuminate the sample at high spatial frequency content. Combining adaptive optics with a custom deconvolution algorithm, we obtain a resolution improvement of a factor < 2.5. Our Scattering Assisted Imaging (SAI, M. Leonetti et al., Sci. Rep. 9:4591 (2019)) provides an effective solution to increase the resolution when long working distance optics are needed.

Paper Details

Date Published: 11 March 2020
Proc. SPIE 11248, Adaptive Optics and Wavefront Control for Biological Systems VI, 112480H (11 March 2020); doi: 10.1117/12.2535590
Show Author Affiliations
Marco Leonetti, Istituto Italiano di Tecnologia (Italy)
Alfonso Grimaldi, Istituto Italiano di Tecnologia (Italy)
Silvia Ghirga, Istituto Italiano di Tecnologia (Italy)
Giancarlo Ruocco, Istituto Italiano di Tecnologia (Italy)
Giuseppe Antonacci, Univ. Gent (Belgium)
IMEC (Belgium)

Published in SPIE Proceedings Vol. 11248:
Adaptive Optics and Wavefront Control for Biological Systems VI
Thomas G. Bifano; Sylvain Gigan; Na Ji, Editor(s)

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