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Proceedings Paper

The study of focused ultrasound effect to increase the penetration of light for photodynamic therapy of deeper tissue
Author(s): Seung Hee Han; Won Seok Chang; Jae Hyuk Kim
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Paper Abstract

This study investigates that the light source can be transmitted deeper for photodynamic treatment of deep locations using the biological correlations of Focused Ultrasound and tissue. we used the phenomenon that Focused Ultrasound induced changes in tissue structure. Ultrasound interacts with tissue through both thermal and non-thermal mechanisms and generates a variety of biological effects. We measured 1. Monte Carlo Simulation to measurement of the relationship between the constitutional deformation of the tissue and the transmittance of the light source 2. Measurement of the effect of the scattering coefficient. 3. Measurement of biological tissue by constitution modification with biological characteristics of ultrasound. a chest tissue phantom was sampled, and a system was developed with FUS and Laser. In conclusion, we could detect the possibility that the light source could penetrate deeper into the region of the tissue after the FUS was irradiated.

Paper Details

Date Published: 1 October 2019
PDF: 3 pages
Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791X (1 October 2019); doi: 10.1117/12.2534937
Show Author Affiliations
Seung Hee Han, Univ. Health Network (Canada)
Univ. of Toronto (Canada)
Won Seok Chang, Yonsei Univ. College of Medicine (Korea, Republic of)
Jae Hyuk Kim, SAMSUNG Electronics Co., Ltd. (Korea, Republic of)


Published in SPIE Proceedings Vol. 11079:
Medical Laser Applications and Laser-Tissue Interactions IX
Lothar D. Lilge; Carsten M. Philipp, Editor(s)

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