Share Email Print
cover

Proceedings Paper

Synergy of light and sound for high-resolution optical focusing, imaging, and stimulation through and within scattering media (Conference Presentation)

Paper Abstract

Light, in many ways, is an ideal form of electromagnetic waves to probe and treat biological tissues. But biomedical optical techniques encounter an inevitable trade-off between resolution and penetration depth due to the strong scattering of light in tissue; existing microscopic optical modalities seldom can see beyond the so-called optical diffusion limit (~1 mm for human skin). In this talk, we summarize our endeavors in the past years of using the synergy of light and sound to achieve high-resolution optical imaging, focusing, and neuron activation in thick biological tissue based on the synergy of light and sound and optical wavefront shaping. Limitations, potential applications, and further direction are also discussed. The work has been supported by the National Natural Science Foundation of China (no. 81671726 and no. 81627805), the Hong Kong Research Grant Council (no. 25204416), the Hong Kong Innovation and Technology Commission (no. ITS/022/18), and the Shenzhen Science and Technology Innovation Commission (no. JCYJ20170818104421564).

Paper Details

Date Published: 9 September 2019
PDF
Proc. SPIE 11122, Ultrafast Nonlinear Imaging and Spectroscopy VII, 111220Q (9 September 2019);
Show Author Affiliations
Puxiang Lai, The Hong Kong Polytechnic Univ. (Hong Kong, China)
Zhipeng Yu, The Hong Kong Polytechnic Univ. (Hong Kong, China)
Huanhao Li, The Hong Kong Polytechnic Univ. (Hong Kong, China)
Tianting Zhong, The Hong Kong Polytechnic Univ. (Hong Kong, China)
Zihao Li, The Hong Kong Polytechnic Univ. (Hong Kong, China)


Published in SPIE Proceedings Vol. 11122:
Ultrafast Nonlinear Imaging and Spectroscopy VII
Zhiwen Liu; Demetri Psaltis; Kebin Shi, Editor(s)

© SPIE. Terms of Use
Back to Top
PREMIUM CONTENT
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?
close_icon_gray