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Highly efficient MRI through multi-shot echo planar imaging
Author(s): Congyu Liao; Xiaozhi Cao; Jaejin Cho; Zijing Zhang; Kawin Setsompop; Berkin Bilgic
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Paper Abstract

Multi-shot echo planar imaging (msEPI) is a promising approach to achieve high in-plane resolution with high sampling efficiency and low T2* blurring. However, due to the geometric distortion, shot-to-shot phase variations and potential subject motion, msEPI continues to be a challenge in MRI. In this work, we introduce acquisition and reconstruction strategies for robust, high-quality msEPI without phase navigators. We propose Blip Up-Down Acquisition (BUDA) using interleaved blip-up and -down phase encoding, and incorporate B0 forward-modeling into Hankel structured low-rank model to enable distortion- and navigator-free msEPI. We improve the acquisition efficiency and reconstruction quality by incorporating simultaneous multi-slice acquisition and virtual-coil reconstruction into the BUDA technique. We further combine BUDA with the novel RF-encoded gSlider acquisition, dubbed “BUDA-gSlider”, to achieve rapid high isotropic resolution MRI. Deploying BUDA-gSlider with model-based reconstruction allows for distortion-free whole-brain 1mm isotropic T2 mapping in ~1 minute. It also provides whole-brain 1mm isotropic diffusion imaging with high geometric fidelity and SNR efficiency. We finally incorporate sinusoidal “wave” gradients during the EPI readout to better use coil sensitivity encoding with controlled aliasing.

Paper Details

Date Published: 9 September 2019
PDF: 13 pages
Proc. SPIE 11138, Wavelets and Sparsity XVIII, 1113818 (9 September 2019); doi: 10.1117/12.2527183
Show Author Affiliations
Congyu Liao, Athinoula A. Martinos Ctr. for Biomedical Imaging (United States)
Harvard Medical School (United States)
Xiaozhi Cao, Zhejiang Univ. (China)
Jaejin Cho, Athinoula A. Martinos Ctr. for Biomedical Imaging, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
Zijing Zhang, Athinoula A. Martinos Ctr. for Biomedical Imaging, Massachusetts General Hospital (United States)
Zhejiang Univ. (China)
Kawin Setsompop, Athinoula A. Martinos Ctr. for Biomedical Imaging, Massachusetts General Hospital (United States)
Harvard Medical School (United States)
Berkin Bilgic, Athinoula A. Martinos Ctr. for Biomedical Imaging, Massachusetts General Hospital (United States)
Harvard Medical School (United States)


Published in SPIE Proceedings Vol. 11138:
Wavelets and Sparsity XVIII
Dimitri Van De Ville; Manos Papadakis; Yue M. Lu, Editor(s)

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