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Proceedings Paper

Blood oxygenation in buried flaps: a bi-layer reconstruction
Author(s): Audrey Dot; Anne Planat-Chrétien; Mathieu Perriollat; Michel Berger; Rodolphe Lartizien; Maxime Henry; Georges Bettega; Jean-Luc Coll
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Paper Abstract

Blood oxygenation in depth is a critical parameter to be monitored in many clinical applications. We are developing a pre-clinical instrument to monitor oxygenation up to 1.5 cm deep in biological tissues. The measures, based on time of ight, are in vivo, non invasive and without injection of any contrast agent. Developments have been implemented in a tomographic reconstruction algorithm to make it reconstruct chromophores by layers. These developments are presented here along with simulations we used to set up the algorithm. Buried aps on 20 pigs were undergone for pre-clinical tests of our reconstruction algorithm and instrument.

Paper Details

Date Published: 11 July 2019
PDF: 3 pages
Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107427 (11 July 2019);
Show Author Affiliations
Audrey Dot, INSERM, Univ. Grenoble Alpes (France)
Anne Planat-Chrétien, Univ. Grenoble Alpes, CEA-LETI (France)
Mathieu Perriollat, Univ. Grenoble Alpes, CEA-LETI (France)
Michel Berger, Univ. Grenoble Alpes, CEA-LETI (France)
Rodolphe Lartizien, Ctr. Hospitalier Annecy Genevois (France)
Maxime Henry, Univ. Grenoble Alpes (France)
Georges Bettega, Ctr. Hospitalier Annecy Genevois (France)
Jean-Luc Coll, Univ. Grenoble Alpes (France)

Published in SPIE Proceedings Vol. 11074:
Diffuse Optical Spectroscopy and Imaging VII
Hamid Dehghani; Heidrun Wabnitz, Editor(s)

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