Proceedings Paper
Laser irradiation induces mitochondrial dysfunction in hepatic cells| Format | Member Price | Non-Member Price |
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Paper Abstract
Laser irradiation has been recognized as a promising tool across a number of biomedical applications. However, understanding the molecular mechanisms and cellular responses remains incomplete. Here, we investigated the mechanism involved in the apoptotic process in human hepatic cells under laser irradiation. Our data show that the laser-mediated alternation of mitochondrial membrane potential leads apoptosis in Huh7 and Alexander cells. Contrary, HepG2 cells are resistant to laser induced cell death. The observed link between mitochondrial membrane potential and cytotoxicity could be a fundamental phenomenon in laser-induced cell apoptosis.
Paper Details
Date Published: 22 July 2019
PDF: 4 pages
Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 1107911 (22 July 2019); doi: 10.1117/12.2527110
Published in SPIE Proceedings Vol. 11079:
Medical Laser Applications and Laser-Tissue Interactions IX
Lothar D. Lilge; Carsten M. Philipp, Editor(s)
PDF: 4 pages
Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 1107911 (22 July 2019); doi: 10.1117/12.2527110
Show Author Affiliations
Anna Lynnyk, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Barbora Smolková, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Mariia Uzhytchak, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Daria Egorova, ITMO Univ. (Russian Federation)
Andrei Kulikov, ITMO Univ. (Russian Federation)
Barbora Smolková, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Mariia Uzhytchak, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Daria Egorova, ITMO Univ. (Russian Federation)
Andrei Kulikov, ITMO Univ. (Russian Federation)
Mariia Lunova, Institute for Clinical and Experimental Medicine (Czech Republic)
Šárka Kubinová, Institute of Experimental Medicine (Czech Republic)
Alexandr Dejneka, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Oleg Lunov, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Šárka Kubinová, Institute of Experimental Medicine (Czech Republic)
Alexandr Dejneka, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Oleg Lunov, Institute of Physics of the CAS, v.v.i. (Czech Republic)
Published in SPIE Proceedings Vol. 11079:
Medical Laser Applications and Laser-Tissue Interactions IX
Lothar D. Lilge; Carsten M. Philipp, Editor(s)
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