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Proceedings Paper

Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures
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Paper Abstract

A multivariate method integrating time-domain and space-domain techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical scattering and absorption properties in tissues. The concept is theoretically demonstrated by Monte-Carlo simulations in the homogenous case, and then applied on twolayer liquid phantoms. The deviations from nominal values are typically less than 6% for absorption coefficients in both layers

Paper Details

Date Published: 11 July 2019
PDF: 4 pages
Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110740A (11 July 2019); doi: 10.1117/12.2527032
Show Author Affiliations
Lin Yang, Physikalisch-Technische Bundesanstalt (Germany)
Technische Univ. Berlin (Germany)
Pranav Lanka, Politecnico di Milano (Italy)
Heidrun Wabnitz, Physikalisch-Technische Bundesanstalt (Germany)
Rinaldo Cubeddu, Politecnico di Milano (Italy)
Thomas Gladytz, Physikalisch-Technische Bundesanstalt (Germany)
Sanathana Konugolu Venkata Sekar, Politecnico di Milano (Italy)
Dirk Grosenick, Physikalisch-Technische Bundesanstalt (Germany)
Antonio Pifferi, Politecnico di Milano (Italy)
Rainer Macdonald, Physikalisch-Technische Bundesanstalt (Germany)
Technische Univ. Berlin (Germany)

Published in SPIE Proceedings Vol. 11074:
Diffuse Optical Spectroscopy and Imaging VII
Hamid Dehghani; Heidrun Wabnitz, Editor(s)

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