
Proceedings Paper
Blood plasma separation using microfluidic guiding channel in a continuous fashionFormat | Member Price | Non-Member Price |
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Paper Abstract
Since plasma proteins are varied depending on diseases states, its continuous monitoring has been considered as effective diagnostic tool. In this study, a simple and efficient method for separate plasma and red blood cells (RBCs) from blood sample is proposed with a microfluidic device. To separate plasma in continuous way, microfluidic guiding channel is designed by connecting two channels with different heights in parallel, and employs inertial force and Zweifach–Fung bifurcation law. Due to its unique geometry, most RBCs flowed inside wall region with higher height. Then, plasma is collected from center region with lower height. As a result, the efficiency of plasma separation is achieved over 90 %. Furthermore, it is remained constant, even up to high value of 40% hematocrit. In the near future, the proposed method will be integrated with a lab-on-a-chip for diagnosing diseases.
Paper Details
Date Published: 19 July 2019
PDF: 3 pages
Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 110731R (19 July 2019); doi: 10.1117/12.2526676
Published in SPIE Proceedings Vol. 11073:
Clinical and Preclinical Optical Diagnostics II
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)
PDF: 3 pages
Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 110731R (19 July 2019); doi: 10.1117/12.2526676
Show Author Affiliations
Published in SPIE Proceedings Vol. 11073:
Clinical and Preclinical Optical Diagnostics II
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)
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